是計(jì)算公式嗎
Odds ratio,
假定我們要鑒別一個(gè)基因(或者標(biāo)記位點(diǎn)SNP)有兩個(gè)等位基因(等位):記為
Allele 1
Allele 2
Allele 1 Allele 2
病例 對(duì)照
A B
C D
odds 值在病例和對(duì)照可以計(jì)算如下:
病例Odds = A (A + B)/ B (A + B) = A / B
對(duì)照Odds = C (C + D) / D (C + D) = C / D
那么在這一點(diǎn)的OR值可以計(jì)算如下:
Odds Ratio = (A / B)/(C / D) = A D/ B C